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The menstrual cycle and mood disorders

¹Department of Research Assessment and Training, New York State Psychiatric Institute, NY 10032.

Journal of Affective Disorders

|October 1, 1993

Summary

The menstrual cycle can worsen mood disorders in women. The premenstrual phase increases vulnerability to severe depression or worsening symptoms for some individuals.

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Area of Science:

Psychiatry
Reproductive Endocrinology
Women's Health

Background:

Mood disorders affect many women, with symptom fluctuations often noted.
The influence of the menstrual cycle on mood disorders requires further investigation.

Purpose of the Study:

To examine the relationship between the menstrual cycle and mood disorder symptom severity.
To identify specific phases of the menstrual cycle associated with increased mood disorder vulnerability.

Main Methods:

Review and synthesis of existing data on menstrual cycle phase and mood disorder course.
Analysis of patient data (details not specified in abstract).

Main Results:

A subset of women with mood disorders exhibit increased vulnerability during the premenstrual phase.
This phase is associated with the onset of severe depressive episodes or exacerbation of existing depression.

Conclusions:

The premenstrual phase of the menstrual cycle is a critical period for mood disorder management in susceptible women.
Further research is warranted to understand the mechanisms and develop targeted interventions.

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