Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Experimental and predicted dual oximetry variability

D H Wong1, P Weir, C K Mahutte

  • 1Department of Anesthesiology, University of California, Irvine.

Journal of Clinical Monitoring
|September 1, 1993
PubMed
Summary

Predicting the precision of dual oximetry (SaO2-SvO2) is best achieved using a root mean square error with a correction term. This method accurately estimates the standard deviation of the difference for combined oxygen saturation measurements.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cannabis use and cognitive biases in people with first-episode psychosis and their siblings.

Psychological medicine·2024
Same author

Exploring the underwater life in transitional environments: Benthic foraminifera, ostracods, and dinoflagellate cysts - Biotic trends and EcoQS assessment in the Mar Piccolo of Taranto (Ionian sea, southern Italy).

Marine environmental research·2024
Same author

Tobacco use in first-episode psychosis, a multinational EU-GEI study.

Psychological medicine·2023
Same author

A method for bivalve shells characterization by FT-IR photoacoustic spectroscopy as a tool for environmental studies.

MethodsX·2022
Same author

Reply to: Neurosurgical education in Ireland; a conference and medical student experiences.

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2020
Same author

The influence of risk factors on the onset and outcome of psychosis: What we learned from the GAP study.

Schizophrenia research·2020

Area of Science:

  • Medical Devices
  • Clinical Measurement
  • Physiology

Background:

  • Accurate measurement of arterial oxygen saturation (SaO2) and mixed venous oxygen saturation (SvO2) is crucial in patient monitoring.
  • Understanding the combined variability of SaO2 and SvO2 is essential for interpreting clinical data.
  • Existing methods for predicting the precision of combined variables may not be sufficiently accurate.

Purpose of the Study:

  • To evaluate if individual bias and precision of SaO2 and SvO2 can predict the bias and precision of the combined variable (SaO2-SvO2).
  • To develop and validate a predictive model for the standard deviation of the difference in dual oximetry measurements.

Main Methods:

  • Simultaneous measurement of SaO2 and SvO2 in 238 datasets from 55 patients.

Related Experiment Videos

  • Comparison of three methods for predicting the standard deviation of the difference: simple sum, root mean square (RMS) error, and RMS error with correction term.
  • Derivation of a new equation incorporating a correction term to account for measurement non-independence.

    • Main Results:

    • The observed bias for SaO2, SvO2, and (SaO2-SvO2) were 0.17, -1.76, and 1.94, respectively.
    • The observed standard deviation of the difference for (SaO2-SvO2) was 5.12.
    • The RMS error with correction term method accurately predicted the observed standard deviation of the difference, while simple sum and basic RMS error methods showed significant deviations.

    Conclusions:

    • The bias of a combined variable (SaO2-SvO2) is the difference between the individual biases of SaO2 and SvO2.
    • The RMS error with correction term provides the best prediction for the standard deviation of the difference in dual oximetry.
    • The principles are applicable to other combined variables like (PaCO2-EtCO2) gradients.