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Duodenal manometry in postobstructive enteropathy in infants with a transient enterostomy
J P Cezard1, G Cargill, C Faure
1Service de Gastroentérologie Pédiatrique et de Chirurgie, Hôpital Robert Debre, Paris, France.
Journal of Pediatric Surgery
|November 1, 1993
Summary
Neonatal intestinal obstruction can cause chronic motility issues in children, leading to postobstructive enteropathy. This study found altered migrating motor complex patterns and reduced motility index in affected children.
Area of Science:
- Pediatric Gastroenterology
- Neonatal Surgery
- Motility Disorders
Background:
- Neonatal intestinal obstruction can lead to transient enterostomy.
- Postobstructive enteropathy is a potential complication.
- Understanding motility alterations is crucial for management.
Purpose of the Study:
- To investigate intestinal motility in children with transient enterostomy post-obstruction.
- To correlate motility abnormalities with clinical presentation and enteropathy severity.
- To elucidate the pathophysiology of postobstructive enteropathy.
Main Methods:
- Studied 11 children with transient enterostomy due to various neonatal obstructions.
- Assessed motility using barium small intestine transit and duodenal manometry.
- Classified patients into clinical groups based on nutritional support and feeding tolerance.
Main Results:
- Abnormal inert marker transit times correlated with clinical groups and manometric findings.
- Manometry revealed absent or abnormal phase III of the migrating motor complex (MMC).
- Reduced motility index was observed in patients with postobstructive enteropathy.
Conclusions:
- Postobstructive enteropathy is characterized by chronic alterations in intestinal motility.
- Prenatal or postnatal obstructions induce these motility changes.
- Findings confirm motility dysfunction as a key factor in this condition.