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Preampullary congenital duodenal obstruction in a father and son
C E Mitchell1, D G Marshall, W D Reid
1Division of Pediatric Surgery, St Joseph's Health Centre, London, Ontario, Canada.
Insights
This report details a rare case of second-generation duodenal obstruction, where a father and son both experienced preampullary duodenal obstruction. This familial occurrence of duodenal obstruction is exceptionally uncommon.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Medical Genetics
Background:
- Duodenal obstruction in infants can arise from various congenital anomalies.
- Annular pancreas and duodenal stenosis are known causes of upper gastrointestinal obstruction.
Observation:
- A male infant presented in 1960 with preampullary total duodenal obstruction due to combined annular pancreas and duodenal stenosis.
- The patient underwent a gastroduodenostomy for surgical correction.
Findings:
- In 1989, the same individual's son was born with preampullary duodenal atresia, a similar condition.
- The son underwent a successful duodeno-duodenostomy performed by the same pediatric surgeon.
Implications:
- This case represents a rare instance of familial, or second-generation, duodenal obstruction.
- The findings suggest a potential genetic component or predisposition to congenital duodenal anomalies.
Abstract:
This is the report of an infant seen on June 25, 1960 with preampullary total duodenal obstruction caused by a combined annular pancreas and duodenal stenosis above the ampulla. A gastroduodenostomy was performed. In December 1989, he fathered a 1,700-g boy with preampullary duodenal atresia. A duodeno-duodenostomy was performed successfully by the same pediatric surgeon. Second-generation duodenal obstruction is rare; to our knowledge, there are no other cases.