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Flow dynamics in the human aorta

K B Chandran1

  • 1Department of Biomedical Engineering, University of Iowa, Iowa City 52242-1527.

Journal of Biomechanical Engineering
|November 1, 1993
PubMed
Summary
This summary is machine-generated.

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Editorial.

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See all related articles

This review explores complex blood flow dynamics within the aorta, highlighting secondary flows and their impact on atherosclerosis and distal blood vessel perfusion. Understanding aortic flow is crucial for cardiovascular health.

Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Fluid Dynamics

Background:

  • The aorta is the primary systemic artery, distributing blood from the left ventricle.
  • Its complex geometry (curvature, branches, taper) influences blood flow patterns.
  • Wall shear stress in the aorta is implicated in the development of atherosclerosis.

Purpose of the Study:

  • To review current understanding of complex blood flow dynamics in the aorta.
  • To discuss the role of secondary flows in aortic hemodynamics.
  • To explore the implications of aortic flow for atherosclerosis and distal perfusion.

Main Methods:

  • Review of theoretical and experimental investigations.
  • Analysis of findings from transesophageal echocardiography.

Related Experiment Videos

  • Examination of data from magnetic resonance velocity mapping.

    • Main Results:

    • Evidence confirms secondary flows exist even in the descending aorta.
    • Complex flow patterns are influenced by the aorta's intricate geometry.
    • Secondary flows affect perfusion in major branches like the superior mesenteric and renal arteries.

    Conclusions:

    • Understanding aortic blood flow is critical for elucidating atherosclerosis.
    • Secondary flows play a significant role in distal blood vessel perfusion.
    • Advanced imaging techniques provide new insights into aortic hemodynamics.