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[Melkersson-Rosenthal syndrome. A case report]
M Pellegrino1, M R D'Altilia, M Pastore
1Divisione di Pediatria, Ospedale Casa Sollievo della Sofferenza, IRCCS, San Giovanni Rotondo, Foggia.
Minerva Pediatrica
|October 1, 1993
Summary
Melkersson-Ros Rosenthal syndrome (MRS) is a rare condition characterized by facial palsy, folded tongue, and lip swelling. This report details a 13-year-old boy presenting with the complete triad of MRS symptoms.
Area of Science:
- Neurology
- Genetics
- Immunology
Background:
- Melkersson-Rosenthal syndrome (MRS) is a rare, idiopathic disorder.
- Classical MRS presents with recurrent facial palsy, lingua plicata (folded tongue), and orofacial edema (swelling).
- Diagnosis can be challenging due to incomplete symptom presentation, with complete triads reported in only 25-30% of cases.
Observation:
- A case study of a 13-year-old boy with the classical triad of Melkersson-Rosenthal syndrome is presented.
- The patient exhibited all three hallmark symptoms, facilitating diagnosis.
Findings:
- The report discusses the pathology, clinical manifestations, and management strategies for MRS.
- Potential contributing factors, such as food allergies or additive intolerances, are explored.
Implications:
- This case highlights the importance of recognizing the complete triad for timely MRS diagnosis.
- Further research into the etiology, including potential triggers like diet, is warranted for improved management.
- Understanding MRS pathogenesis is crucial for developing targeted therapies.