Fish-oil supplementation reduces intestinal hyperproliferation in persons at risk for colon cancer

Hyperproliferation in the upper compartments of colonic crypts is associated with an increased risk for colon cancer. A recent short-term, double-blind, placebo-controlled study found that fish-oil supplementation (8 g/day) reduced the rate of proliferation in the upper crypt cells of patients with a history of colonic polyps.