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Glucagon-aided reduction of intussusception

J K Fisher, D R Germann

    Radiology
    |January 1, 1977
    PubMed
    Summary

    Intramuscular glucagon aided barium enema reduction in two ileocolic intussusception cases. Combining glucagon with barium enema may improve nonoperative reduction success rates for intussusception.

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    Area of Science:

    • Pediatric Gastroenterology
    • Radiology

    Background:

    • Intussusception is a common surgical emergency in children.
    • Nonoperative reduction, typically via barium enema, is the standard treatment.
    • Failure of initial reduction attempts can necessitate alternative strategies.

    Observation:

    • Two pediatric patients with ileocolic intussusception underwent attempted reduction.
    • Standard therapeutic barium enema failed to achieve reduction in both cases.
    • Intramuscular glucagon was administered prior to a repeat barium enema.

    Findings:

    • Glucagon administration facilitated successful reduction of intussusception in both patients.
    • The combination of glucagon and repeat barium enema proved effective.
    • This approach offers a potential adjunct to standard nonoperative reduction.

    Implications:

    • Intramuscular glucagon may enhance the success rate of nonoperative intussusception reduction.
    • This method could be considered when initial barium enema reduction fails.
    • Further research is warranted to validate glucagon's role in intussusception management.

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