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Relapsing polychondritis, another cause for a "salmon patch"

S M Tucker1, J V Linberg, H M Doshi

  • 1Department of Ophthalmology, West Virginia University School of Medicine, Morgantown 26506-9193.

Annals of Ophthalmology
|October 1, 1993
PubMed
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Relapsing polychondritis can cause orbital and conjunctival masses. This case highlights a unique "salmon patch" conjunctival lesion, suggesting it be considered in differential diagnoses.

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Pathology

Background:

  • Relapsing polychondritis is a rare systemic autoimmune disease characterized by progressive destruction of cartilaginous structures.
  • Ocular manifestations of relapsing polychondritis, while documented, are typically limited to scleritis, uveitis, and episcleritis.

Observation:

  • A patient with established relapsing polychondritis developed an orbital mass followed by a distinct conjunctival lesion resembling a "salmon patch."
  • Histopathological examination of both masses revealed similar inflammatory infiltrates with reactive lymphoid hyperplasia.

Findings:

  • Both the orbital and conjunctival masses demonstrated a positive response to a brief course of systemic corticosteroid therapy.
  • This report is the first to describe a conjunctival "salmon patch" lesion in the context of relapsing polychondritis.

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Implications:

  • Conjunctival "salmon patch" lesions should be included in the differential diagnosis for patients presenting with ocular findings and a history of relapsing polychondritis.
  • This case expands the spectrum of ocular manifestations associated with relapsing polychondritis, emphasizing the need for comprehensive evaluation.