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Related Experiment Videos

[Titanium plates for mandibular reconstruction and radiotherapy]

J Pinsolle1, H Demeaux, E Phan

  • 1Service de Chirurgie Maxillo-Faciale, CHU, Bordeaux.

Annales De Chirurgie Plastique Et Esthetique
|April 1, 1993
PubMed
Summary

Titanium mandibular reconstruction plates show satisfactory mid-term tolerance following radiotherapy for cancer surgery. Radiotherapy, particularly with parallel opposing fields, minimizes tissue overdosage and likely does not affect plate integrity.

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Area of Science:

  • Oncology
  • Biomaterials Science
  • Radiation Oncology

Context:

  • Mandibular reconstruction plates are utilized in patients undergoing cancer surgery.
  • Titanium plates are increasingly used in cranio-maxillofacial reconstructions.
  • Radiotherapy is a common adjuvant treatment following cancer resection.

Purpose:

  • To evaluate the dosimetry and mid-term tolerance of titanium mandibular reconstruction plates after radiotherapy.
  • To assess the impact of radiotherapy on titanium implants in cancer patients.
  • To determine the safety and efficacy of concurrent radiotherapy with titanium mandibular plates.

Summary:

  • Twenty patients with titanium mandibular reconstruction plates received radiotherapy (mean dose 60 Gy).
  • Dosimetry was calculated using 3D treatment planning, and tolerance was assessed clinically and radiologically at 6 months post-treatment.

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  • Mid-term tolerance was favorable, with only two failures (e.g., osteomyelitis, healing issues) observed.

    • Impact:

    • Radiotherapy with parallel opposing fields reduced tissue overdosage to approximately 5%.
    • Titanium mandibular reconstruction plates demonstrated very satisfactory mid-term tolerance.
    • The findings suggest radiotherapy likely has no adverse effect on the tolerance of titanium plates.