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Mitral regurgitation due to intermittent prosthetic valvular dysfunction

C J Carlson, J J Collins, I S Ockene

    Chest
    |January 1, 1977
    PubMed
    Summary

    A Harken disk valve malfunctioned due to excessive wear, causing mitral regurgitation two years after replacement. This case highlights the risk of prosthetic valve degeneration and the need for careful monitoring.

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    Area of Science:

    • Cardiovascular Surgery
    • Biomedical Engineering
    • Materials Science

    Background:

    • Prosthetic heart valves are crucial for treating valvular heart disease.
    • Mechanical valves, like the Harken disk valve, offer durability but can be subject to wear.
    • Understanding long-term prosthetic valve performance is essential for patient outcomes.

    Observation:

    • A patient experienced paraprosthetic aortic insufficiency and signs of prosthetic mitral valve dysfunction 2.5 years post-surgery.
    • Hemodynamic abnormalities and intermittent mitral regurgitation were detected via catheterization and imaging.
    • The excised Harken disk valve showed significant wear, including loss of disk substance and rim notching.

    Findings:

    • This report details a second instance of Harken disk valve malfunction attributed to undue disk wear.

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  • Severe wear of the prosthetic mitral valve disk was the primary cause of regurgitation.
  • Structural integrity of the valve struts and sewing ring remained intact, indicating isolated disk degeneration.

    • Implications:

    • This case underscores the potential for mechanical prosthetic valve disk degeneration over time.
    • It highlights the importance of recognizing and investigating intermittent prosthetic valve dysfunction.
    • Further research into the long-term wear characteristics of prosthetic valve components is warranted.