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Clozapine in the treatment of psychotic refractory depression

D Dassa1, A Kaladjian, J M Azorin

  • 1Department of Psychiatry, Timone Hospital, Marseille, France.

A 40-year-old woman suffering from major depression with psychotic features was unresponsive to conventional therapy. After the administration of a wide range of drug treatments and ECT, she received clozapine. Depressive symptoms improved and psychotic features disappeared. It is suggested that clozapine could be efficient in psychotic refractory depression.

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