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Myasthenia gravis associated with small-cell carcinoma of the lung
J Fujita1, I Yamadori, Y Yamaji
1First Department of Internal Medicine, Kagawa Medical School, Japan.
Chest
|February 1, 1994
Abstract:
A 49-year-old man complained of a 3-month history of progressive generalized muscle weakness. He was diagnosed as having small-cell lung carcinoma at the same time. He received an intravenous injection of edrophonium chloride with remarkable improvement of muscle strength. Electromyographic studies revealed a compound muscle action potential that decreased after repetitive stimulation. These findings were considered representative of myasthenia gravis (MG), and inconsistent with Eaton-Lambert syndrome. The appearance of MG with small-cell lung carcinoma seems to be very rare, but possible.