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Published on: May 15, 2013
Parental smoking and other risk factors for wheezing bronchitis in children
E Rylander1, G Pershagen, M Eriksson
1Department of Epidemiology, Karolinska Institute, Stockholm, Sweden.
Insights
Parental smoking significantly increases the risk of childhood wheezing bronchitis and asthma. Reducing environmental exposures like smoke and ensuring longer breastfeeding can dramatically lower incidence.
Area of Science:
- Pediatric respiratory health
- Environmental epidemiology
- Public health
Background:
- Wheezing bronchitis and asthma are common respiratory illnesses in young children.
- Identifying preventable risk factors is crucial for primary prevention strategies.
Purpose of the Study:
- To investigate etiologic factors for wheezing bronchitis and asthma in children up to four years of age.
- To assess the impact of parental smoking and other environmental factors on childhood respiratory illnesses.
Main Methods:
- Population-based case-control study.
- 199 hospitalized children (cases) and 351 controls were interviewed.
- Data collected via home interviews regarding parental smoking, heredity, infections, and feeding practices.
Main Results:
- Parental smoking showed a relative risk of 1.8 (27% population attributable proportion), strongest with maternal smoking in infants under 18 months.
- Atopic heredity, recurrent upper respiratory infections, and short breastfeeding (<3 months) interacted with parental smoking.
- Combined environmental factors (smoking, short breastfeeding, pets) accounted for 43% of cases, with greater impact in younger children.
Conclusions:
- Parental smoking is a major modifiable risk factor for childhood wheezing and asthma.
- Environmental factors significantly influence respiratory health in early childhood.
- Primary prevention focusing on reducing parental smoking and optimizing breastfeeding can substantially decrease the incidence of these conditions.
Abstract:
A population-based case-control study was performed to investigate etiologic factors for wheezing bronchitis and asthma in children up to four years of age. A total of 199 children hospitalized for the first time with these diagnoses at a major hospital in Stockholm in 1986-1988 constituted the cases, 351 children from the catchment area of the hospital were used as controls. Information on known and suspected risk factors was obtained through home interviews with a parent. Parental smoking was associated with a relative risk of 1.8 (95% confidence interval 1.3-2.6) corresponding to a population attributable proportion of 27%. The strongest association was seen for maternal smoking and children below 18 months of age. Other major risk factors included atopic heredity, recurrent upper respiratory tract infections and breast-feeding less than 3 months, which appeared to interact multiplicatively with parental smoking. The environmental factors had a stronger influence in the youngest age group, and the overall attributable proportion associated with parental smoking, short breast-feeding period and exposure to pets in the household was 43%. It is clear that successful primary prevention could dramatically reduce the incidence of wheezing bronchitis in children.
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