[Sequences resembling fragments of mitochondrial DNA in the human genome: features of evolution]

Mitochondrial-like sequences and their homologues from primate mitochondria are investigated to define direction and rate of evolution, time of integration into nuclear genome. The analysis showed that mito-like sequences differ from mitochondrial homologues by high level of symmetria of two chains of DNA. Besides that, difference between mito-like and Homo sapiens sequences in their GC-contents is found. Apparently there is GC-pressure of nuclear genome region, being the place of integration of mito-like sequence, that brings about equalization of GC-contents in nuclear region and mito-like sequences. Properties of descent mitochondrial sequence play important role in the difference of mito-like and Homo sapiens sequences also.