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[Tetrazepam in the treatment of acute cervical syndrome. Randomized double-blind pilot study comparing tetrazepam and
E Salzmann1, O Wiedemann, L Löffler
1Sanofi-Winthrop GmbH, Medizinische Abteilung, München.
Fortschritte Der Medizin
|December 10, 1993
Abstract
Methods:
In a double-blind study, 20 ambulatory patients with acute painful restriction of mobility of the cervical spine and overall marked impairment were treated for seven days with tetrazepam (150 mg or a lower dose from the third day onward) or placebo. Paracetamol was permitted in addition if required. Test criteria: The main criterion of efficacy was a summed score of three parameters: pain, restriction of mobility, and general impairment.
Results:
The difference between the groups was statistically highly significant (p = 0.005). Tolerability was adjudged to be "very good" for the placebo group, and, on average, "good" for the tetrazepam group.