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Left ventricular function during dynamic exercise in untrained and moderately trained subjects

M U Brandao1, M Wajngarten, E Rondon

  • 1Heart Institute, University Hospital, University of Sao Paulo Medical School, Brazil.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|November 1, 1993
PubMed
Summary
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Exercise training significantly enhances peak diastolic filling rate but does not alter systolic function during exercise. This indicates that metabolic acidosis from exercise does not impede systolic function in healthy individuals.

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Sports Medicine

Background:

  • Understanding the impact of exercise training on cardiac function is crucial for optimizing athletic performance and cardiovascular health.
  • Left ventricular function is a key indicator of the heart's ability to meet metabolic demands during physical activity.

Purpose of the Study:

  • To investigate the effects of exercise training on left ventricular (LV) function at rest, anaerobic threshold (AT), and peak exercise (PE).
  • To determine if metabolic acidosis during exercise limits systolic function.

Main Methods:

  • Doppler echocardiography and radionuclide ventriculography were used to assess LV function in 12 untrained and 13 trained healthy subjects.
  • Measurements were taken at rest, AT, and PE to evaluate diastolic and systolic parameters.

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Main Results:

  • Trained subjects exhibited higher end-diastolic and stroke volumes at rest compared to untrained subjects.
  • Ejection fraction increased significantly from rest to PE in both groups, with no intergroup differences.
  • Peak diastolic filling rate significantly increased during exercise, showing a greater rise in trained individuals.
  • Systolic function, measured by the percent variation of minimal systolic counts, decreased significantly at AT and PE relative to rest.

Conclusions:

  • Exercise training leads to a significant improvement in peak diastolic filling rate.
  • Systolic function during exercise is not significantly altered by training, and metabolic acidosis does not appear to limit it.