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Value of whole-cell antigen extracts for serologic detection of Helicobacter pylori
S M Salama1, J N Wefuan, S Shiro-Koulla
1Department of Medical Microbiology and Infectious Diseases, University of Alberta, Edmonton, Canada.
Journal of Clinical Microbiology
|December 1, 1993
Abstract:
Whole-cell protein extracts of Helicobacter pylori strains were evaluated by enzyme-linked immunosorbent assay to detect immunoglobulin G antibody against H. pylori in 113 patients with upper gastrointestinal complaints. These antigen preparations were of value for detecting infection by H. pylori in patients with high antibody titers (> or = 12,800), whereas for patients with lower titers, the results were inconclusive.