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Related Experiment Videos

Childhood primary pulmonary neoplasms

B J Hancock1, M Di Lorenzo, S Youssef

  • 1Section of Pediatric General Surgery, Hôpital Sainte-Justine, Montreal, Quebec, Canada.

Journal of Pediatric Surgery
|September 1, 1993
PubMed
Summary

Pediatric lung neoplasms, though rare, require prompt diagnosis and surgical treatment. Complete resection offers an excellent prognosis for most children with these unusual tumors.

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Area of Science:

  • Pediatric Oncology
  • Pulmonary Medicine
  • Thoracic Surgery

Background:

  • Primary endobronchial or pulmonary parenchymal neoplasms are rare in children.
  • Diagnosis often involves persistent symptoms like cough and fever, with radiographic abnormalities.

Purpose of the Study:

  • To describe the clinical presentation, diagnosis, treatment, and outcomes of primary lung neoplasms in children.
  • To emphasize the importance of early surgical intervention for pediatric pulmonary tumors.

Main Methods:

  • Retrospective review of nine children diagnosed with primary endobronchial or pulmonary neoplasms.
  • Diagnostic methods included chest x-rays, computed tomography (CT) scans, bronchoscopy, and biopsy.
  • Treatment involved thoracotomy with pulmonary resection or laser resection.

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Main Results:

  • The average age at diagnosis was 9 years, with common symptoms including cough and fever.
  • Pathologic diagnoses varied, including bronchial carcinoid, mucoepidermoid carcinoma, inflammatory pseudotumor, fibrosarcoma, and rhabdomyosarcoma.
  • Seven of nine children are alive and disease-free post-surgery; one died from rhabdomyosarcoma, and one experienced local recurrence.

Conclusions:

  • Pulmonary neoplasms in children encompass a diverse range of pathologies, with 76% being malignant in reported series.
  • Early investigation and surgical resection are crucial for favorable outcomes.
  • While most pediatric lung tumors have an excellent prognosis with complete surgical removal, malignancies other than bronchial adenomas carry significant mortality.