Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The painful, non-indurated chancre

K E Andersen

    Acta Dermato-Venereologica
    |January 1, 1978
    PubMed
    Summary

    Primary syphilis chancres can be painful and lack induration, contrary to common textbook descriptions. This study highlights potential diagnostic challenges due to these atypical presentations in venereology.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The epidemic of methylisothiazolinone contact allergy in Europe: follow-up on changing exposures.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2019
    Same author

    Sociodemographic factors do not have a large influence on adherence to topical treatment in patients with psoriasis.

    The British journal of dermatology·2019
    Same author

    Use of topical antipsoriatic drugs in Denmark: a nationwide drug utilization study.

    The British journal of dermatology·2018
    Same author

    A smartphone application supporting patients with psoriasis improves adherence to topical treatment: a randomized controlled trial.

    The British journal of dermatology·2018
    Same author

    Factors associated with combined hand and foot eczema.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2016
    Same author

    Repeated monthly epicutaneous challenges with diphenylcyclopropenone result in a clinically reproducible level of contact allergy in de novo sensitized individuals.

    The British journal of dermatology·2016

    Area of Science:

    • Dermatology
    • Infectious Diseases
    • Venereology

    Background:

    • Primary syphilis is a sexually transmitted infection caused by Treponema pallidum.
    • The classic presentation of a primary syphilitic chancre is a painless, indurated ulcer.
    • Existing medical literature may not fully capture the spectrum of syphilitic chancre presentations.

    Purpose of the Study:

    • To evaluate the clinical presentation of primary syphilis chancres in male patients.
    • To compare observed clinical findings with descriptions in venereology textbooks.
    • To identify potential discrepancies that could impact diagnosis.

    Main Methods:

    • Review of medical records for 20 consecutive male patients diagnosed with primary syphilis.
    • Comparative analysis of patient data against information from 23 venereology textbooks.
    • Clinical assessment of chancre characteristics, including pain and induration.

    Main Results:

    • Syphilitic chancres were observed to be painful in some cases.
    • The characteristic induration was absent in a subset of the reviewed cases.
    • Textbook descriptions were found to be potentially misleading regarding chancre presentation.

    Conclusions:

    • The clinical presentation of primary syphilis can deviate from classic textbook descriptions.
    • Painful and non-indurated chancres represent a possible variation in primary syphilis.
    • Clinicians should be aware of atypical chancre presentations to avoid diagnostic delays.

    Related Experiment Videos