A novel chromosomal abnormality detected in a case of acute myelomonocytic leukemia

¹Department of Pediatrics, University Federico II, Naples, Italy.

|February 1, 1994

Abstract:

A not yet recorded translocation, t(3:17)(q21;q23), detected in a case of acute myelomonocytic leukemia, is reported. In spite of an aggressive cytotoxic chemotherapy, the disease showed a rapid fatal course, confirming the dismal prognostic significance of structural, 'primary' chromosomal abnormalities in acute leukemias.

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