Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Motion perception in optic neuropathy

J J Barton1, M Rizzo

  • 1Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City.

Neurology
|February 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polished but pointless? Assessing the potential of gold and silver-alloy IUDs versus copper-only devices in a large multinational cohort (EURAS-LCS12).

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2026
Same author

Case Report: Spontaneous pneumomediastinum in a patient with MDA5-positive dermatomyositis and severe pulmonary fibrosis.

Frontiers in medicine·2025
Same author

Longitudinal validation of the PROFFIT questionnaire to assess financial toxicity in cancer patients.

Journal of cancer policy·2025
Same author

Preliminary insights on the daily rhythm of CRP and IL-6 in athletic horses.

Journal of equine veterinary science·2025
Same author

The genomic landscape of metastatic clear-cell renal cell carcinoma and its prognostic value: a comprehensive analysis of a large real-world clinico-genomic database.

ESMO open·2025
Same author

Marked blastomere herniation is the only post-thaw morphological characteristic associated with a reduced pregnancy rate for in vitro produced equine blastocysts.

Theriogenology·2025
Same journal

Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

Neurology·2026
Same journal

Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

Neurology·2026
Same journal

At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

Neurology·2026
Same journal

Cerebral Artery Pulsatility, Premorbid Blood Pressure, and Small Vessel Disease on Brain Imaging: A Population-Based Study.

Neurology·2026
Same journal

Genetic Risk for Alzheimer Disease, Midlife Hypertension, and Dementia: The ARIC Neurocognitive Study.

Neurology·2026
Same journal

What is the Relevance of Neuron-Tumor Interactions in Malignant CNS Tumors?

Neurology·2026
See all related articles

Patients with optic neuropathy often have impaired motion perception, even with normal vision. This study found defective motion processing in eight of 15 eyes, independent of visual acuity or luminance sensitivity.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Visual Perception

Background:

  • Optic neuropathy can affect visual processing.
  • Motion perception and flicker fusion are thought to rely on the M-channel.
  • Previous research has not fully elucidated the specific deficits in motion perception associated with optic neuropathy.

Purpose of the Study:

  • To investigate motion perception deficits in patients with optic neuropathy.
  • To determine if impaired motion perception is linked to visual acuity or luminance sensitivity.
  • To explore the relationship between motion perception and critical flicker fusion in optic neuropathy.

Main Methods:

  • Assessed motion perception using a global coherent motion discrimination task with varying noise levels.

Related Experiment Videos

  • Evaluated visual acuity using Snellen charts.
  • Measured luminance sensitivity by attenuating display signals.
  • Compared motion perception and critical flicker fusion.

    • Main Results:

    • Eight out of 15 eyes with optic neuropathy showed defective motion processing.
    • Defects in motion perception were not correlated with visual acuity (11/15 eyes had 20/20 or better).
    • Impaired motion perception was also independent of luminance sensitivity.
    • Motion perception and critical flicker fusion were found to be dissociable, challenging existing theories.

    Conclusions:

    • Motion perception deficits are common in optic neuropathy and are not solely due to reduced visual acuity or luminance sensitivity.
    • The findings suggest that motion perception and critical flicker fusion may rely on distinct neural pathways, not exclusively the M-channel.
    • This double dissociation provides new insights into the neural basis of visual processing in optic neuropathies.