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Carbamazepine (Tegretol)-induced thrombocytopenia
Y Shechter1, B Brenner, E Klein
1Hematology Institute, Ramabam Medical Center, Haifa, Israel.
Vox Sanguinis
|January 1, 1993
Abstract:
A case of carbamazepine-induced thrombocytopenia is reported. The patient, a 38-year-old female, developed thrombocytopenia 10 days after receiving 400 mg carbamazepine daily. The presence of an anti-IgG carbamazepine-dependent platelet-reactive antibody was documented. Using flow cytometry, the drug-induced antibody was detected at a drug concentration as low as 10(-6) M.