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Updated: Aug 11, 2026

Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model
Published on: June 18, 2013
Stimulation of taurine efflux from human placental tissue by a hypoosmotic challenge
D B Shennan1, S A McNeillie, D E Curran
1Hannah Research Institute, Ayr.
The fractional release of taurine from preloaded human placental tissue fragments was stimulated by a hypoosmotic challenge. This stimulation could not be attributed to a change in the Na+ gradient or the ionic strength of the medium. We suggest that taurine fluxes may play a role in placental cell volume regulation.
The fractional release of taurine from preloaded human placental tissue fragments was stimulated by a hypoosmotic challenge. This stimulation could not be attributed to a change in the Na+ gradient or the ionic strength of the medium. We suggest that taurine fluxes may play a role in placental cell volume regulation.
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