Related Experiment Video
Updated: Aug 11, 2026

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging
Published on: June 8, 2017
Magnetic resonance imaging of unusual intracranial infections
S Falcone1, R M Quencer, M J Post
1Department of Radiology, University of Miami School of Medicine, FL 33101.
Abstract:
We review the etiologic agents, epidemiology, pathogenesis, pathology, clinical manifestations, and imaging features of several unusual intracranial infections that have not been discussed elsewhere in this issue. The central nervous system (CNS) infections discussed are Creutzfeldt-Jakob disease (CrJaD), neurosyphilis, primary amebic meningoencephalitis (PAM), granulomatous amebic encephalitis (GAE), cerebral amebiasis, and cerebral hydatid disease.
Insights
This review covers rare central nervous system infections, including Creutzfeldt-Jakob disease and amebic encephalitis. Understanding these unusual agents, their spread, and symptoms is crucial for diagnosis.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Unusual intracranial infections are often overlooked in standard reviews.
- A comprehensive understanding of rare CNS pathogens is essential for accurate diagnosis and treatment.
Purpose of the Study:
- To review the etiologic agents, epidemiology, pathogenesis, pathology, clinical manifestations, and imaging features of several uncommon CNS infections.
- To provide a consolidated resource for less frequently encountered intracranial infections.
Main Methods:
- Literature review focusing on specific rare CNS infections.
- Synthesis of information on causative agents, disease progression, and diagnostic findings.
Main Results:
- Detailed discussion of Creutzfeldt-Jakob disease (CrJaD).
- Exploration of neurosyphilis, primary amebic meningoencephalitis (PAM), granulomatous amebic encephalitis (GAE), cerebral amebiasis, and cerebral hydatid disease.
- Emphasis on characteristic clinical and imaging features for each condition.
Conclusions:
- Early recognition of these unusual infections is critical for patient outcomes.
- Familiarity with diverse etiologies and presentations aids in timely diagnosis of rare CNS diseases.
Related Concept Videos
Magnetic Resonance Imaging
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Brain Imaging
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Imaging Studies for Cardiovascular System IV: CMRI
Imaging Studies IV: Magnetic Resonance Imaging
Brain Abscess l: Introduction

