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Pityriasis versicolor

¹Department of Dermatology, University of Gothenburg, Sahlgren's Hospital, Sweden.

Seminars in Dermatology

|December 1, 1993

Summary

Pityriasis versicolor, caused by Pityrosporum ovale, is treatable with topical or oral antifungals. Oral treatments offer high efficacy and compliance, with prophylactic schedules reducing high recurrence rates.

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Area of Science:

Dermatology
Mycology

Background:

Pityrosporum ovale is a lipophilic yeast, part of normal skin flora and a cause of pityriasis versicolor.
Pityriasis versicolor is characterized by predisposing factors leading to recurrence and chronicity.

Purpose of the Study:

To review current topical and systemic treatment options for pityriasis versicolor.
To evaluate the effectiveness of various antifungal agents and prophylactic strategies.

Main Methods:

Review of topical treatments including propylene glycol, imidazoles, antidandruff shampoos, ciclopiroxolamine, and terbinafine.
Analysis of systemic treatments such as short-term oral ketoconazole, itraconazole, and fluconazole.
Assessment of prophylactic treatment schedules to prevent recurrence.

Main Results:

Topical treatments like propylene glycol, imidazoles, and newer antifungals show effectiveness.
Short-term oral antifungal therapy is highly effective with minimized side effects and improved patient compliance.
Prophylactic regimens, such as monthly ketoconazole, are effective in preventing high recurrence rates.

Conclusions:

Both topical and systemic antifungal treatments are viable for pityriasis versicolor.
Oral therapy presents advantages in efficacy, safety, and compliance for treating pityriasis versicolor.
Prophylaxis is crucial for managing the chronic and recurrent nature of pityriasis versicolor.

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