[The model and results of intervention trial of stroke risk factors in Changsha]

To develop an effective method for minimizing the incidence and mortality of cerebrovascular disease, we studied the sample population of intervention community (8,052 subjects) and control community (8,065 subjects) in Changsha. 2,631 subjects in the intervention community and 2,733 subjects in the control community with age more than 35 years were enrolled for a cohort study from January 1, 1986 to December 31, 1990. The annual incidence of stroke was 315/10(5) in the control community and 220/10(5) in the intervention community. The annual incidence of stroke was significantly lower in the intervention community than in the control community (P < 0.01). The incidence of stroke in 1990 dropped by 66.4% compared to that in 1986 in the intervention community. But, in the control community it dropped by 9.7%. The change of the mortality and incidence of stroke in the two communities was similar.