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Rheumatoid pseudotumor of urinary bladder simulating carcinoma

H H Berman, A J Wilets

    Urology
    |January 1, 1977
    PubMed
    Summary
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    A rare case of rheumatoid nodule in the urinary bladder presented as cancer. This finding is unprecedented in medical literature, highlighting the diverse manifestations of rheumatoid arthritis.

    Area of Science:

    • Rheumatology
    • Uropathology

    Background:

    • Rheumatoid arthritis is a chronic autoimmune disease.
    • Rheumatoid nodules are common extra-articular manifestations.
    • Urinary bladder involvement is exceptionally rare.

    Observation:

    • A 49-year-old female patient with seropositive rheumatoid arthritis presented with hematuria.
    • Cystoscopic examination revealed a bladder lesion mimicking carcinoma.
    • The lesion was surgically resected for evaluation.

    Findings:

    • Microscopic examination confirmed the lesion as a rheumatoid nodule.
    • This represents the first reported instance of a rheumatoid nodule in the urinary bladder.
    • The nodule's histological features were consistent with rheumatoid disease.

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    Implications:

    • This case expands the known spectrum of rheumatoid arthritis manifestations.
    • It underscores the importance of considering rheumatoid nodules in bladder lesions, especially in RA patients.
    • Further research may explore the pathogenesis and diagnostic challenges of such rare presentations.