Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lipoprotein subclasses in genetic studies: the Berkeley data set

R M Krauss1, P T Williams, P J Blanche

  • 1Life Sciences Division, Lawrence Berkeley Laboratory, University of California, Berkeley.

Genetic Epidemiology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electronic health record reveals community-level cardiometabolic health benefits associated with 10 years of community-based participatory research.

Public health·2024
Same author

A comparison of product yields and inorganic content in process streams following thermal hydrolysis and hydrothermal processing of microalgae, manure and digestate.

Bioresource technology·2015
Same author

Associations between diet and cardiometabolic risk among Yup'ik Alaska Native people using food frequency questionnaire dietary patterns.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2015
Same author

Sex differences in obesity prevalence and cardiometabolic factors among Western Alaska Native people.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2014
Same author

Effect of process conditions on the steam reforming of ethanol with a nano-Ni/SiO2 catalyst.

Environmental technology·2012
Same author

Two stages catalytic pyrolysis of refuse derived fuel: production of biofuel via syncrude.

Bioresource technology·2010

This study analyzed lipid and lipoprotein subclasses in 301 individuals from 27 families to understand inheritance patterns. Data included LDL and HDL size subclasses and apolipoprotein A-I levels.

Area of Science:

  • Biochemistry
  • Genetics
  • Cardiovascular Health

Background:

  • Lipid and lipoprotein subclasses are key indicators of cardiovascular risk.
  • Understanding the heritability of these subclasses is crucial for personalized medicine.

Purpose of the Study:

  • To investigate the inheritance patterns of LDL and HDL size subclasses.
  • To analyze the relationship between lifestyle factors and lipoprotein subclasses.

Main Methods:

  • Nondenaturing gradient gel electrophoresis for LDL and HDL size subclasses.
  • Radial immunodiffusion for apolipoprotein A-I measurement.
  • Questionnaires for lifestyle factors (medications, hormones, smoking, alcohol).

Main Results:

Related Experiment Videos

  • Collected comprehensive data on lipids, lipoproteins, and subclasses from 301 individuals in 27 kindreds.
  • Established a dataset (Berkeley data set) for further genetic and lifestyle analyses.
  • Included measurements of LDL and HDL size subclasses and apolipoprotein A-I.

    • Conclusions:

    • The Berkeley data set provides a foundation for studying the genetic and environmental influences on lipoprotein subclass inheritance.
    • Further analysis will elucidate the heritability of specific lipoprotein subclasses and their clinical implications.