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Correlation analysis of twin data with repeated measures based on generalized estimating equations
J S Grove1, L P Zhao, F Quiaoit
1Biostatistics Program, School of Public Health, University of Hawaii, Honolulu 96826.
Abstract:
Repeated measures allow additional tests of common assumptions in twin correlation analysis. Analysis of log serum triglyceride level in NHLBI male twins using generalized estimating equations disclosed that the mean and variance shifted across exams, presumably because of changes in laboratory practice.
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