Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurological state, infarct size and clinical outcome are related to early platelet count decrease in stroke

E D'Erasmo1, M Acca, D Pisani

  • 1II Clinica Medica, University of Rome La Sapienza, Italy.

Gerontology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Palatal myoclonus with tinnitus treated as a psychogenic disorder for 35-years.

L'Encephale·2022
Same author

SARS-CoV-2 mRNA booster vaccine-associated lichenoid drug eruption.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

An ancient, Antarctic-specific species complex: large divergences between multiple Antarctic lineages of the tardigrade genus Mesobiotus.

Molecular phylogenetics and evolution·2022
Same author

A recurring blistering eruption on the palms.

Clinical and experimental dermatology·2021
Same author

Pfizer-BioNTech SARS-CoV-2 mRNA vaccine-associated erythema multiforme.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same author

A case of bullous pemphigoid after the SARS-CoV-2 mRNA vaccine.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021
Same journal

Nature-based Virtual Reality for Depression in Alzheimer's Disease: Protocol of a Pilot Randomized Controlled Trial.

Gerontology·2026
Same journal

A Pilot Study of a Multicomponent Interventions in Acute Geriatric Care: Effects on Functional Outcomes and Mobility.

Gerontology·2026
Same journal

Geriatrics co-management of the vulnerable older surgical patient.

Gerontology·2026
Same journal

Title: Same Day Discharge in Primary Total Joint Arthroplasty in Octogenarians: A Case Series and Narrative Review of Optimization Strategies and Perioperative Outcomes.

Gerontology·2026
Same journal

Emotional Reactivity to Daily Physical Symptoms in Adulthood and Old Age: The Role of Different Facets of Social Support.

Gerontology·2026
Same journal

Sex Differences in the Development of a Multidimensional Fall Risk Index for Older Adults.

Gerontology·2026
See all related articles

Early reduction in platelet count in ischemic stroke patients correlates with worse neurological impairment, larger infarcts, and poorer clinical outcomes. This finding highlights the prognostic value of monitoring platelet levels post-stroke.

Area of Science:

  • Neurology
  • Hematology
  • Cerebrovascular disease

Background:

  • Ischemic stroke is a leading cause of long-term disability.
  • Predictive markers for stroke severity and outcomes are crucial for patient management.
  • The role of platelet dynamics in acute ischemic stroke requires further elucidation.

Purpose of the Study:

  • To investigate the correlation between early platelet count reduction and key stroke indicators.
  • To assess the relationship between circulating platelet decrease and neurological impairment, infarct size, and clinical outcomes in ischemic cerebral infarction.

Main Methods:

  • Observational study design.
  • Analysis of patient data from established ischemic cerebral infarction cases.
  • Measurement of circulating platelet counts and neurological status.

Related Experiment Videos

Main Results:

  • A significant correlation was observed between early platelet count reduction and initial neurological impairment.
  • Platelet consumption/accumulation in the infarct area, indicated by decreased platelet count, is linked to infarct extension.
  • Reduced platelet counts are associated with poorer clinical outcomes in ischemic stroke patients.

Conclusions:

  • Early decrease in platelet count serves as a potential biomarker for stroke severity.
  • Platelet dynamics play a significant role in the pathophysiology and prognosis of ischemic stroke.
  • Monitoring platelet levels may aid in predicting clinical outcomes and guiding therapeutic strategies.