Mucinous adenocarcinoma arising in a neovagina
Related Experiment Video
Updated: Nov 8, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
A Munkarah1, J M Malone, H D Budev
1Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Hutzel Hospital, Detroit, Michigan 48201.
Abstract:
The development of carcinoma in a neovagina is a rare occurrence. A case of mucinous adenocarcinoma of a neovagina is presented. A neovagina was formed in 1945 to correct a congenital anomaly. Subsequently the patient developed a chronic rectovaginal fistula. It is thought that the mucinous adenocarcinoma developed as a result of chronic inflammation secondary to the fistula. Although rare, development of a malignancy in ectopic tissue can occur. Clinicians need to be aware of this as they follow these patients.
Related Concept Videos
Vagina
Candidiasis
Mucosal Barrier of the Stomach
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...
Cellular Adaptation IV: Dysplasia and Metaplasia
External Female Genitals