Genetic loadings in schizophrenia: a dermatoglyphic study
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Updated: Oct 31, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
Published on: June 15, 2011
R S Balgir1, R S Murthy, N N Wig
1Department of Hematology, Regional Medical Research Center, Bhubaneswar, Orissa, India.
Abstract:
Finger and palmar dermatoglyphics of 120 male and 120 female schizophrenics with and without a family history of schizophrenia in first-degree relatives were studied in the northwestern part of India. Patients were selected according to specific diagnostic criteria. Significant dermatoglyphic differences were observed for fingerprint patterns, total finger ridge counts and 'atd' angle between the schizophrenics with and those without a positive family history of schizophrenia, suggesting a strong "genetic loading" (i.e., hereditary factors) in familial cases of schizophrenia. Dermatoglyphic features of isolated schizophrenics also significantly differed from those of controls, thus indicating the involvement of genetic factors in the etiology of schizophrenia.
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