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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

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Related Experiment Video

Updated: Jul 22, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

[Ultrasonic cyclodialysis in glaucoma surgery in aphakia]

V P Erichev, F E Fridman, M B Kodzov

    Vestnik Oftalmologii
    |January 1, 1993
    PubMed
    Summary

    A novel ultrasonic cyclodialysis surgery effectively treats aphakic eye glaucoma by normalizing intraocular pressure. This minimally invasive procedure improves fluid drainage and reduces humor production, offering a safe treatment option.

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    Last Updated: Jul 22, 2026

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    Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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    Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

    Published on: July 7, 2023

    Area of Science:

    • Ophthalmology
    • Surgical Innovation
    • Glaucoma Research

    Context:

    • Aphakic eye glaucoma presents unique treatment challenges.
    • Current surgical options may have limitations.
    • Low-frequency ultrasound offers a new therapeutic modality.

    Purpose:

    • To evaluate the efficacy and safety of ultrasonic cyclodialysis for treating aphakic eye glaucoma.
    • To assess the impact of this novel surgical method on intraocular pressure.
    • To elucidate the mechanism of action for the observed hypotensive effect.

    Summary:

    • Fifteen patients with aphakic eye glaucoma underwent ultrasonic cyclodialysis.
    • A six-month follow-up revealed stable normalization of intraocular pressure.
    • The procedure is characterized by its minimally invasive nature and smooth postoperative recovery.

    Impact:

    • Ultrasonic cyclodialysis demonstrates potential as an effective and safe surgical treatment for aphakic eye glaucoma.
    • The findings suggest improved aqueous humor outflow and reduced production as key mechanisms.
    • This approach offers a promising alternative with a favorable safety profile.