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Changes in transthoracic electrical impedance at high altitude

R S Hoon, V Balasubramanian, S C Tiwari

    British Heart Journal
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

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    Transthoracic electrical impedance measurements may help detect early signs of high altitude pulmonary edema. A significant drop in impedance was observed in individuals developing altitude sickness symptoms.

    Area of Science:

    • Physiology
    • Altitude Medicine

    Background:

    • High altitude pulmonary edema (HAPE) is a serious condition affecting individuals at elevated altitudes.
    • Transthoracic electrical impedance (impedance) is a non-invasive measure related to fluid volume within the chest.

    Observation:

    • 121 healthy volunteers were studied at sea-level and high altitude (3658m).
    • Groups included rapid ascent via aircraft, slow road ascent, permanent residents, and temporary residents.
    • Serial impedance measurements were taken, particularly in those developing altitude sickness.

    Findings:

    • Subjects developing high altitude sickness showed a significant decrease in impedance, especially those with severe symptoms.
    • A case of acute pulmonary edema showed a marked drop in impedance, which normalized after treatment.

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  • Asymptomatic individuals and those with slow acclimatization exhibited minimal impedance changes.

    • Implications:

    • Transthoracic electrical impedance measurement shows promise as a tool for early detection of incipient high altitude pulmonary edema.
    • This non-invasive method could aid in monitoring individuals at risk in high-altitude environments.
    • Further research could validate impedance monitoring for HAPE prevention and management.