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Polycystic ovarian syndrome. Evidence for an autoimmune mechanism in some cases
C J van Gelderen1, M L Gomes dos Santos
1Department of Obstetrics and Gynaecology, Baragwanath Hospital, Johannesburg, South Africa.
The Journal of Reproductive Medicine
|May 1, 1993
Abstract:
Antiovarian autoantibodies localized to the granulosa cells were detected in 50% of a group of eight patients diagnosed with polycystic ovarian syndrome. An analogy is drawn to other endocrinopathies characterized by hypersecretion of hormones, notably thyroid and adrenal, and a pathogenetic mechanism involving stimulating antibody is postulated.