Automated perimetric changes following panretinal photocoagulation in diabetic retinopathy

Sixty eyes--30 with severe nonproliferative diabetic retinopathy (NPDR) and 30 with proliferative diabetic retinopathy (PDR)--underwent argon laser panretinal photocoagulation (PRP). Static perimetry (Humphrey automated visual field analyzer 630, Threshold Prog Central 30-1 and Peri 30/60-1) was done 1 day before and 6 weeks after the initial laser treatment. One day before treatment, the fields of the NPDR and PDR eyes differed mainly in the central field affection: the PDR eyes had more localized areas of markedly decreased retinal sensitivity and, therefore, a higher initial mean deviation value and higher corrected pattern standard deviation values. However, peripheral retinal sensitivity was equally depressed in the NPDR and PDR eyes. Six weeks after treatment, central retinal sensitivity had significantly improved in all of the eyes, although more so in the eyes with severe NPDR. This study suggests that static-perimetry-guided PRP is an effective treatment for diabetic retinopathy, especially severe NPDR.