Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optic nerve decompression improves hemodynamic parameters in papilledema

R A Mittra1, R C Sergott, P M Flaharty

  • 1Neuro-Ophthalmology Service, Wills Eye Hospital, Philadelphia, PA.

Ophthalmology
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decreased ACKR3 (CXCR7) function causes oculomotor synkinesis in mice and humans.

Human molecular genetics·2019
Same author

Effect of screening for syphilis on the management of patients with cerebrovascular disease.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015
Same author

Entropion in children with isolated peripheral facial nerve paresis.

Eye (London, England)·2012
Same author

Orbitofacial neurofibromatosis: clinical characteristics and treatment outcome.

Eye (London, England)·2011
Same author

Primer on visual field testing, electroretinography, and other visual assessments for patients treated with vigabatrin.

Acta neurologica Scandinavica. Supplementum·2011
Same author

Understanding and interpreting vision safety issues with vigabatrin therapy.

Acta neurologica Scandinavica. Supplementum·2011
Same journal

Value of 10-2 Visual Field Testing for Detecting Progression in Patients with Glaucoma.

Ophthalmology·2026
Same journal

Comparative Five-Year Risks of Systemic Complications with Biologic versus Conventional Therapy in Non-infectious Uveitis.

Ophthalmology·2026
Same journal

Diverse Conjunctival Adverse Events Associated with Tisotumab Vedotin.

Ophthalmology·2026
Same journal

The Answer Is Blowing in the Wind: Uncovering Hidden Glaucoma Risk Factors.

Ophthalmology·2026
Same journal

Nonsteroidal Anti-inflammatory Drug Use Reduces the Risk of Age-Related Macular Degeneration in Electronic Health Record Analysis: Signal or Solution?

Ophthalmology·2026
Same journal

Metastasis of Nasopharyngeal Squamous Cell Carcinoma to the Angle.

Ophthalmology·2026
See all related articles

Optic nerve sheath decompression (ONSD) may improve vision in pseudotumor cerebri (PTC) by reversing impaired retrobulbar circulation and reducing ischemia. This study examined Doppler imaging parameters before and after ONSD surgery.

Area of Science:

  • Ophthalmology
  • Neurology
  • Vascular Imaging

Background:

  • Chronic papilledema due to pseudotumor cerebri (PTC) can lead to vision loss.
  • Retrobulbar circulation impairment is suspected in PTC-related visual deficits.

Purpose of the Study:

  • To evaluate changes in color Doppler imaging parameters post-optic nerve sheath decompression (ONSD) for chronic papilledema in PTC patients.
  • To correlate these hemodynamic changes with visual outcomes.

Main Methods:

  • Color Doppler imaging of ophthalmic, central retinal, and short posterior ciliary arteries performed pre- and post-ONSD.
  • Pulsed Doppler spectrum analysis to assess blood flow velocities and pulsatility index.

Main Results:

Related Experiment Videos

  • Pre-operative decreased blood flow velocities in retrobulbar arteries were observed, correlating with visual acuity.
  • Post-ONSD, significant improvements in Doppler parameters were noted in eyes with improved vision.
  • Ophthalmic artery diastolic velocity increased, while central retinal artery parameters showed no significant change post-surgery.
  • Conclusions:

    • Impaired retrobulbar circulation and ischemia may contribute to vision loss in chronic papilledema.
    • ONSD may improve visual function by ameliorating these ischemic processes.
    • Color Doppler imaging can help assess the impact of ONSD on retrobulbar hemodynamics.