Pheochromocytoma manifested as noncardiogenic pulmonary edema

We have reported the case of a woman who had repeated episodes of noncardiogenic pulmonary edema as the initial clinical manifestation of pheochromocytoma. She had no evidence of heart failure or paroxysmal blood pressure changes. In a review of the English-language literature, we found only five other cases in which pheochromocytoma was associated with noncardiogenic pulmonary edema. Our report emphasizes the need to consider pheochromocytoma in the differential diagnosis of noncardiogenic pulmonary edema. Awareness of this unusual clinical presentation will increase the likelihood of early diagnosis and surgical cure.