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Intraoral acinic cell carcinoma
1Department of Oral and Maxillofacial Surgery, Beilinson Medical Center, Petah Tiqva, Israel.
Annals of Dentistry
|January 1, 1993
Summary
Acinic cell carcinomas in minor salivary glands are slow-growing tumors. Wide local excision is effective, though recurrence is possible, highlighting the need for long-term monitoring.
Area of Science:
- Oral pathology
- Surgical oncology
Background:
- Acinic cell carcinoma (ACC) is a malignant neoplasm arising from salivary glands.
- Minor salivary glands (MSGs) represent a less common site for ACC compared to major salivary glands.
Observation:
- Report of three cases of ACC specifically affecting the minor salivary glands of the oral cavity.
- Clinical presentation included slow-growing, asymptomatic tumors.
- Treatment involved wide local excision as the primary surgical approach.
Findings:
- Long-term follow-up in the reported cases demonstrated no instances of metastasis.
- One patient experienced a local recurrence of the tumor post-excision.
- ACC generally exhibits potential for late recurrence and metastasis, even years after initial treatment.
Implications:
- Wide local excision is confirmed as a primary treatment modality for oral cavity ACC.
- The long-term efficacy of adjuvant radiotherapy and chemotherapy for ACC remains indeterminate.
- Ongoing surveillance is crucial for patients treated for ACC due to the risk of late recurrence.