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Related Experiment Videos

Edothelin-1 in human skin

H A Bull, P M Dowd

    Dermatology (Basel, Switzerland)
    |January 1, 1993
    PubMed
    Summary
    This summary is machine-generated.

    Endothelin-1 (ET-1), a peptide from endothelium, regulates vascular tone and cellular responses. Recent research explores its role in skin homeostasis and disease, expanding beyond its initial vascular functions.

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    Area of Science:

    • Cardiovascular Biology
    • Molecular Medicine
    • Dermatology

    Background:

    • Endothelin-1 (ET-1) initially identified as an endothelium-derived vasoconstrictor.
    • ET-1's role extends beyond vascular tone, influencing diverse cellular functions.
    • ET-1 is also synthesized in the nervous system and modulates neurotransmission.