Intravascular ultrasonography before and after intervention: in vivo comparison with angiography

To compare the additional capacity of intravascular ultrasonography versus angiography to assess morphologic features and lumen dimension, 37 patients undergoing vascular intervention of the common iliac or superficial femoral artery were studied. A total of 181 ultrasonic cross sections were analyzed (94 before and 87 after intervention).

Before intervention intravascular ultrasonography distinguished normal cross sections (n = 17) from cross sections with a lesion (n = 77): soft (51%) versus hard (31%) lesions, and eccentric (75%) versus concentric (7%) lesions. After intervention intravascular ultrasonography documented dissection (43%), plaque rupture (10%), and internal elastic lamina rupture (8%). A good correlation between ultrasonography and angiography was found for the recognition of eccentric or concentric lesions and dissections. The degree of stenosis was assessed semiquantitatively by visual estimation of the degree of luminal narrowing from the angiograms and intravascular ultrasonic images and was categorized into four classes: (1) normal, (2) less than 50% stenosis, (3) 50% to 90% stenosis, and (4) greater than 90% stenosis. Intravascular ultrasonographic assessment of stenosis was in agreement with angiography in 78% of cases and showed more severe lesions in 22% before intervention. Similar data were observed after intervention, with 72% of results being in agreement and 28% of cases showing more severe lesions. The degree of stenosis was also quantitatively evaluated by computer-aided analysis of the intravascular ultrasonic images. The semiquantitative analysis by intravascular ultrasonography corresponded well with the quantitative analysis done by the computer-aided system. When both echography and angiography suggested that arteries were normal, quantitative intravascular ultrasonography identified lesions that occupied an average of 18% of the cross-sectional area of the vessel.

This in vivo study shows that intravascular ultrasonography is capable of documenting detailed morphologic features. Semiquantitative ultrasonic data correlate closely with those of angiography, albeit stenoses were assessed as more severe on ultrasonography.