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Related Experiment Videos

Aortic pressure estimation with electro-mechanical circulatory assist devices

J F Gardner1, M Ignatoski, U Tasch

  • 1Pennsylvania State University, University Park 16802.

Journal of Biomechanical Engineering
|May 1, 1993
PubMed
Summary

This study introduces an adaptive dynamic observer to estimate aortic pressure during electric ventricular assist device (EVAD) operation. The novel technique accurately estimates pressure, improving EVAD monitoring and patient outcomes.

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Area of Science:

  • Biomedical Engineering
  • Control Systems Engineering
  • Cardiovascular Physiology

Background:

  • Accurate estimation of aortic pressure is crucial for monitoring the performance of ventricular assist devices (VADs).
  • Traditional methods may lack real-time adaptability to changing physiological conditions during VAD support.
  • The Penn State Electric Ventricular Assist Device (EVAD) requires precise feedback for optimal function.

Purpose of the Study:

  • To design, implement, and validate an adaptive dynamic observer for estimating aortic pressure time history.
  • To improve the accuracy and robustness of aortic pressure estimation during EVAD operation.
  • To assess observer performance across a range of physiological operating conditions.

Main Methods:

  • Developed an adaptive dynamic observer using applied voltage and position feedback from the EVAD.

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  • Determined observer gains using experimental data from a mock circulatory system.
  • Incorporated an adaptive scheme for stroke-by-stroke adjustment of observer initial conditions.
  • Tested the system across varying beat rates (56-104 bpm) and aortic pressures (10.7-18.7 kPa).

    • Main Results:

    • The adaptive observer demonstrated satisfactory performance across tested operating conditions.
    • Mean deviation between actual and estimated aortic pressure was 0.41 kPa (3.1 mmHg) during the latter two-thirds of systole.
    • The adaptive scheme improved observer performance by adjusting initial conditions dynamically.

    Conclusions:

    • The developed adaptive dynamic observer is a viable technique for real-time aortic pressure estimation with EVADs.
    • This method offers improved accuracy and adaptability compared to non-adaptive approaches.
    • The findings support the use of advanced control techniques for enhanced VAD monitoring and management.