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Factors affecting the development of skin cancer after scalp irradiation
B Modan1, E Alfandary, D Shapiro
1Department of Clinical Epidemiology, Chaim Sheba Medical Center, Tel Aviv University Medical School, Israel.
Radiation Research
|July 1, 1993
Abstract:
A nested case control study of persons who developed skin cancer after scalp irradiation in childhood revealed two risk factors for the appearance of radiation-induced skin cancer: (a) an apparently higher radiation dose delivered inadvertently, manifested by a higher prevalence of alopecia and radiation dermatitis (RR = 3.4; CI 1.3-8.8); (b) a more frequent exposure to the sun, manifested by summer sunbathing (RR = 2.6; CI 1.1-6.1). These findings may have certain implications with regard to the understanding of radiation-induced cancer, after low-dose radiation exposure, in general.