[Paraneoplastic pemphigus and adenocarcinoma of the colon]

An increased incidence of cancer has been observed in patients with pemphigus and described mostly since the 1970. Lymphoreticular malignancies and thymomas were the most often reported neoplasms. Paraneoplastic pemphigus is a newly described syndrome with specific characteristics. In this report, a patient with pemphigus and colonic adenocarcinoma is described. In this case, clinical and histologic features suggest the diagnosis of paraneoplastic pemphigus which would be for the first time described in association with colonic adenocarcinoma.