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Allergy to Alternaria. I. Clinical aspects

C Granel1, G Tapias, M Valencia

  • 1Hospital Santa Creu i Sant Pau, Unit of Allergy, Barcelona, Spain.

Allergologia Et Immunopathologia
|January 1, 1993
PubMed
Summary

Most patients allergic to Alternaria mould also experience other allergies, frequently to dust mites (D. pteronyssinus) and grass pollen. This highlights the common issue of polysensitization in mould allergy patients.

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Area of Science:

  • Allergology
  • Immunology
  • Respiratory Medicine

Background:

  • Mould allergy, particularly to Alternaria, is a significant health concern.
  • Patients with Alternaria allergy often exhibit co-existing allergic conditions.

Purpose of the Study:

  • To characterize the allergic profile of patients with Alternaria allergy.
  • To compare patients with Alternaria allergy to those with grass pollen and Dermatophagoides pteronyssinus allergy.

Main Methods:

  • Study included 66 patients diagnosed with Alternaria allergy.
  • Allergic sensitization patterns were analyzed.
  • Comparison group included patients allergic to grass pollen and D. pteronyssinus.

Main Results:

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  • 60% of patients had asthma, 40% had rhinitis.
  • Only 29% were exclusively sensitized to Alternaria.
  • 71% were polysensitized, commonly to D. pteronyssinus, grass pollen, Cladosporium, and cat epithelium.

    • Conclusions:

    • Alternaria allergy frequently co-exists with other allergies, indicating polysensitization.
    • Understanding co-sensitization patterns is crucial for effective allergy management.