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Acute lymphoidic leukemia in a patient with thrombocytopenia/absent radii (Tar) syndrome
1Department of Pediatrics, Medical College of Wisconsin, Milwaukee.
Abstract
Purpose:
Patients with thrombocytopenia, absent radii (TAR) syndrome have a spontaneous amelioration of thrombocytopenia after infancy. No individual with the syndrome has been reported to develop subsequent bone marrow disease.
Patients And Methods:
We report a child with TAR syndrome who developed acute lymphoidic leukemia.
Results And Conclusions:
The TAR syndrome may predispose patients to other forms of marrow disease (as do other inherited marrow failure diseases). Additional cases are needed to confirm this hypothesis.