Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Moderate resistance exercise program: its effect in slowly progressive neuromuscular disease

S G Aitkens¹, M A McCrory, D D Kilmer

¹Department of Physical Medicine and Rehabilitation, School of Medicine, University of California, Davis 95616.

Archives of Physical Medicine and Rehabilitation

|July 1, 1993

Summary

This study found that a 12-week moderate resistance exercise program is safe and effective for patients with slowly progressive neuromuscular diseases (NMD). The strengthening program led to significant improvements in muscle strength for both NMD patients and controls.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Deficits in episodic memory are related to uncontrolled eating in a sample of healthy adults.

Appetite·2017

Same author

Food cravings and energy regulation: the characteristics of craved foods and their relationship with eating behaviors and weight change during 6 months of dietary energy restriction.

International journal of obesity (2005)·2007

Same author

Eating patterns and dietary composition in relation to BMI in younger and older adults.

International journal of obesity (2005)·2006

Same author

Systemic lupus erythematosus in a multiethnic US Cohort (LUMINA). XXX: association between C-reactive protein (CRP) gene polymorphisms and vascular events.

Rheumatology (Oxford, England)·2005

Same author

Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level.

Journal of molecular medicine (Berlin, Germany)·2005

Same author

Relative influence of diet and physical activity on cardiovascular risk factors in urban Chinese adults.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity·2003

Area of Science:

Neurology
Rehabilitation Medicine
Exercise Physiology

Background:

Slowly progressive neuromuscular diseases (NMD) often lead to muscle weakness and functional decline.
Resistance exercise is a potential intervention, but its safety and efficacy in NMD populations require investigation.

Purpose of the Study:

To determine the safety and efficacy of a 12-week moderate resistance exercise program in patients with slowly progressive neuromuscular diseases (NMD).

Main Methods:

A 12-week home-based, moderate resistance exercise program using ankle/wrist weights and hand grips was implemented.
Subjects (27 NMD patients, 14 controls) exercised 3 days/week, with one body side randomly selected for training.
Maximal isokinetic and isometric strength were measured at baseline, week 4, and week 12.

Related Experiment Videos

Main Results:

Both NMD and control groups showed significant increases (p < .05) in most strength measures.
Strength gains were similar between exercised and non-exercised limbs within each group.
The exercise program was well-tolerated and demonstrated practicality in the NMD cohort.

Conclusions:

A 12-week submaximal strength training program is safe and practical for individuals with slowly progressive neuromuscular diseases.
This exercise regimen can lead to moderate improvements in measured muscle strength for NMD patients.