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Serum opacity factor of Staphylococcus epidermidis

S H El Tayeb, E M Nasr

    Infection and Immunity
    |January 1, 1977
    PubMed
    Summary

    Three Staphylococcus epidermidis strains create a serum opacity factor that causes cloudiness in blood serum but not in albumin. This factor remains active after heating or aging and functions best in acidic conditions.

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    Area of Science:

    • Microbiology
    • Biochemistry

    Background:

    • Staphylococcus epidermidis is a common bacterium.
    • Understanding bacterial factors is crucial for diagnostics and treatment.

    Purpose of the Study:

    • To investigate the properties of a factor produced by Staphylococcus epidermidis that affects serum opacity.

    Main Methods:

    • Culturing Staphylococcus epidermidis strains.
    • Testing the effect of the produced factor on different sera and albumin.
    • Assessing the factor's stability to heat and age.
    • Determining the optimal pH for factor activity.

    Main Results:

    • Three strains of Staphylococcus epidermidis produced a serum opacity factor.
    • The factor caused opacity in various sera but not in albumin.
    • The opacity factor demonstrated resistance to degradation by heat and aging.
    • The factor was most active in acidic environments.

    Conclusions:

    • Staphylococcus epidermidis can produce a heat- and age-resistant serum opacity factor.
    • This factor's activity is dependent on pH, showing optimal function in acidic conditions.

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