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Endometrial polyp: another benign tumor characterized by 12q13-q15 changes
Cancer Genetics and Cytogenetics
|July 1, 1993
Summary
Cytogenetic analysis of endometrial polyps reveals consistent chromosome changes. This study identifies a new subgroup of benign tumors with rearrangements in chromosome region 12q14-15.
Area of Science:
- Cytogenetics
- Oncology
- Molecular Biology
Background:
- Clustering of chromosomal aberrations in benign tumors can pinpoint genes involved in proliferation.
- Previous cytogenetic studies on endometrial polyps are limited, with a consistent involvement of the 6p21 band noted.
- Endometrial polyps are common benign gynecological tumors.